Description

5-Bromo-6-(2,2,2-trifluoroethoxy)nicotinic acid is a high-value, multi-functional chemical intermediate designed for advanced synthesis. This compound matters for its unique trifluoroethoxy and bromo substitution pattern, which imparts desirable electronic and steric properties to target molecules. Pharmaceutical and agrochemical R&D teams need it as a critical building block for developing novel active ingredients, particularly in the areas of kinase inhibitors and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for targeted cancer therapies and kinase inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for constructing complex heterocyclic systems and functionalized pyridine derivatives.
• Material Science Precursor: Potential use in the synthesis of specialty chemicals, ligands for catalysis, and advanced organic materials.

Basic Information

Product Name	5-Bromo-6-(2,2,2-trifluoroethoxy)nicotinic Acid
CAS No.	1211586-75-2
Molecular Formula	C8H5BrF3NO3
Molecular Weight	300.03 g/mol
Synonyms	5-Bromo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-bromo-6-(2,2,2-trifluoroethoxy)-; 5-Bromo-6-(2,2,2-trifluoroethoxy)nicotinic acid; 1211586-75-2; Nicotinic acid, 5-bromo-6-(2,2,2-trifluoroethoxy)-
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-(2,2,2-trifluoroethoxy)nicotinic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.