Description

5-Fluoro-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for lead optimization and scalable production.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Employed as a molecular probe or scaffold in drug discovery and target identification studies.
• Material Science: Potential precursor for advanced organic electronic materials and ligands in catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and library production.

Basic Information

Product Name	5-Fluoro-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylic Acid
CAS No.	1211586-74-1
Molecular Formula	C7H4FN3O2
Molecular Weight	181.12 g/mol
Synonyms	5-Fluoro-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid; 5-Fluoro-3-carboxy-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-3-carboxylic acid, 5-fluoro-; 1211586-74-1; 5-Fluoro-1H-pyrazolo[3,4-b]pyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.