Description

3-Fluoro-5-Hydroxypyridine-2-Carbonitrile is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. Its unique structure, featuring a nitrile, a hydroxyl, and a fluorine substituent on a pyridine ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-withdrawing groups.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	3-Fluoro-5-Hydroxypyridine-2-Carbonitrile
CAS No.	1211584-91-6
Molecular Formula	C6H3FN2O
Molecular Weight	138.10 g/mol
Synonyms	2-Cyano-3-fluoro-5-hydroxypyridine; 5-Hydroxy-3-fluoropyridine-2-carbonitrile; 3-Fluoro-5-hydroxypicolinonitrile; 3-Fluoro-5-pyridinol-2-carbonitrile; 2-Pyridinecarbonitrile, 3-fluoro-5-hydroxy-; 1211584-91-6; 3-F-5-OH-Py-2-CN
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-Hydroxypyridine-2-Carbonitrile is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to support regulatory filings in target industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.