Description

3-Bromo-2-Cyano-6-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical synthetic intermediate. Its molecular architecture, featuring bromine, cyano, and trifluoromethyl substituents, provides unique reactivity and physicochemical properties essential for advanced chemical synthesis. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic scaffolds and introducing key functional groups.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.
• Functional Group Transformation: The cyano group can be hydrolyzed to carboxylic acids, reduced to amines, or serve as a handle for constructing heterocycles like tetrazoles and triazoles.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Bromo-2-Cyano-6-(Trifluoromethyl)Pyridine
CAS No.	1211583-96-8
Molecular Formula	C7H2BrF3N2
Molecular Weight	250.99 g/mol
Synonyms	2-Cyano-3-bromo-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-3-bromopyridine-2-carbonitrile; 3-Bromo-6-(trifluoromethyl)picolinonitrile; 3-Bromo-2-cyano-6-trifluoromethylpyridine; Pyridine, 3-bromo-2-cyano-6-(trifluoromethyl)-; 1211583-96-8
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Cyano-6-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to supply chain integrity and documentation transparency supports our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.