Description

4-Bromo-3-Fluoro-2-Methylpyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used to create advanced fungicides and herbicides by introducing the bromo-fluoro-methylpyridine moiety into lead structures.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Chemical Biology: Employed as a probe or labeling reagent due to its reactive halogen site for bioconjugation.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Product Name	4-Bromo-3-Fluoro-2-Methylpyridine
CAS No.	1211583-78-6
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	2-Methyl-4-bromo-3-fluoropyridine; 3-Fluoro-2-methyl-4-bromopyridine; 4-Bromo-3-fluoro-2-picoline; Pyridine, 4-bromo-3-fluoro-2-methyl-; 1211583-78-6
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Fluoro-2-Methylpyridine is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. We provide comprehensive analytical data, including HPLC purity, NMR, and GC-MS characterization. Certificates of Analysis (COA) are available for each lot upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.