Description

2-Bromo-3-Chloro-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and halogen substitution pattern makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials, contributing to the development of OLEDs, semiconductors, and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions, enabling the construction of complex biaryl and heterobiaryl structures.
• Chemical Biology & Proteomics: Utilized as a versatile scaffold for designing molecular probes, tags, and inhibitors used in biochemical and cellular studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated pyridine frameworks.

Basic Information

Product Name	2-Bromo-3-Chloro-4-(Trifluoromethyl)Pyridine
CAS No.	1211582-91-0
Molecular Formula	C6H2BrClF3N
Molecular Weight	260.44 g/mol
Synonyms	2-Bromo-3-chloro-4-(trifluoromethyl)pyridine; 3-Chloro-2-bromo-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-2-bromo-3-chloropyridine; Pyridine, 2-bromo-3-chloro-4-(trifluoromethyl)-; 1211582-91-0
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Chloro-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming the product meets your specified requirements. Our commitment to quality assurance and supply reliability supports critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound should be handled and stored under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.