Description

3-Methyl-6-(Trifluoromethyl)Pyridin-2-Amine CAS NO 1211582-57-8 is a high-value, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its structure, featuring both an amine and a trifluoromethyl group, makes it a versatile intermediate for introducing specific pharmacophores and modifying physicochemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes, enzyme inhibitors, and labeled compounds for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis services catering to R&D and scale-up projects requiring fluorinated heterocycles.

Basic Information

Product Name	3-Methyl-6-(Trifluoromethyl)Pyridin-2-Amine
CAS No.	1211582-57-8
Molecular Formula	C7H7F3N2
Molecular Weight	176.14 g/mol
Synonyms	2-Amino-3-methyl-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-3-methylpyridin-2-amine; 3-Methyl-6-trifluoromethylpyridin-2-ylamine; 2-Pyridinamine, 3-methyl-6-(trifluoromethyl)-; 1211582-57-8; 3-Methyl-6-(trifluoromethyl)-2-pyridinamine
EINECS	Contact for details

Quality Control

Our production of 3-Methyl-6-(Trifluoromethyl)Pyridin-2-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by advanced analytical techniques (HPLC, GC, NMR). Our quality system is designed to support regulatory filings and GMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.