Description

2-Bromo-6-Chloro-3-Iodo-Pyridine is a highly functionalized halogenated pyridine derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its value lies in the strategic placement of three distinct halogen atoms, which offer orthogonal reactivity for sequential cross-coupling and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic scaffolds and active ingredients. The product, identified by CAS NO 1211580-38-9, is supplied with a focus on high purity and batch-to-batch consistency to support demanding R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with complex pyridine-based structures.
• Material Science Research: Used in the creation of organic electronic materials, ligands for catalysis, and functional polymers.
• Cross-Coupling Reactions: The bromo, chloro, and iodo substituents provide versatile handles for Suzuki, Stille, Negishi, and Buchwald-Hartwig amination reactions.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes and diagnostic agents.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Bromo-6-Chloro-3-Iodo-Pyridine
CAS No.	1211580-38-9
Molecular Formula	C5H2BrClIN
Molecular Weight	318.34 g/mol
Synonyms	2-Bromo-6-chloro-3-iodopyridine; 3-Iodo-2-bromo-6-chloropyridine; 6-Chloro-2-bromo-3-iodopyridine; Pyridine, 2-bromo-6-chloro-3-iodo-; 1211580-38-9; 2-Br-6-Cl-3-I-pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-Chloro-3-Iodo-Pyridine is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Standard analytical techniques including HPLC, GC, NMR, and mass spectrometry are employed to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing all relevant specifications are available upon request and are integral to our commitment to supply chain transparency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.