Description

4-(Trifluoromethyl)-1H-Pyrazolo-[3,4-B]Pyridin-3-Amine is a high-value heterocyclic organic compound featuring a pyrazolopyridine core substituted with a trifluoromethyl group and an amine. This structure is of significant interest in modern pharmaceutical and agrochemical research due to its potential as a versatile synthetic building block. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrazolopyridine scaffold.
• Chemical Biology Probe: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a building block for advanced organic electronic materials due to its fused heterocyclic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-(Trifluoromethyl)-1H-Pyrazolo-[3,4-B]Pyridin-3-Amine
CAS No.	1211579-79-1
Molecular Formula	C7H5F3N4
Molecular Weight	202.14 g/mol
Synonyms	3-Amino-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine; 4-(Trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-3-amine; 1H-Pyrazolo[3,4-b]pyridin-3-amine, 4-(trifluoromethyl)-; 1211579-79-1; 4-Trifluoromethyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine
EINECS	Contact for details

Quality Control

Every batch of 4-(Trifluoromethyl)-1H-Pyrazolo-[3,4-B]Pyridin-3-Amine is produced and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry to ensure identity and consistency. Certificates of Analysis (COA) are available for all shipments, and we support custom purity requirements for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.