Description

(3-Chloro-5-Fluoropyridin-2-Yl)Methanamine is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated amine structure enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chloro-fluoro-amine motifs into complex target molecules.

Application

• Pharmaceutical Intermediate: A versatile building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials requiring specific amine and halogen functionalities.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	(3-Chloro-5-Fluoropyridin-2-Yl)Methanamine
CAS No.	1211578-98-1
Molecular Formula	C6H6ClFN2
Molecular Weight	160.58 g/mol
Synonyms	1-(3-Chloro-5-fluoropyridin-2-yl)methanamine; 2-(Aminomethyl)-3-chloro-5-fluoropyridine; (3-Chloro-5-fluoro-2-pyridinyl)methanamine; 3-Chloro-5-fluoro-2-pyridinemethanamine; 2-Aminomethyl-3-chloro-5-fluoropyridine; 3-Chloro-5-fluoro-pyridin-2-ylmethylamine; (3-Chloro-5-fluoropyridin-2-yl)methylamine
EINECS	Contact for details

Quality Control

Our (3-Chloro-5-Fluoropyridin-2-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.