Description

6-Chloro-5-(Trifluoromethyl)Pyridin-3-Ol is a high-value fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, makes it an essential intermediate for creating molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often improves efficacy and environmental profile.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Research & Development: A versatile building block for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies and route scouting.
• Liquid Crystal & Electronic Chemicals: Potential intermediate in the synthesis of fluorinated components for electronic applications and display technologies.

Basic Information

Product Name	6-Chloro-5-(Trifluoromethyl)Pyridin-3-Ol
CAS No.	1211578-93-6
Molecular Formula	C6H3ClF3NO
Molecular Weight	197.54 g/mol
Synonyms	3-Hydroxy-6-chloro-5-(trifluoromethyl)pyridine; 6-Chloro-5-(trifluoromethyl)-3-pyridinol; 6-Chloro-5-trifluoromethylpyridin-3-ol; 5-(Trifluoromethyl)-6-chloropyridin-3-ol; 6-Chloro-5-trifluoromethyl-3-hydroxypyridine; 3-Pyridinol, 6-chloro-5-(trifluoromethyl)-; 6-Chloro-5-trifluoromethyl-3-pyridol
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-(Trifluoromethyl)Pyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong alkalis and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤1.0%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.