Description

6-Bromo-5-Nitropyridine-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromo and nitro substituents on the pyridine ring, makes it a versatile precursor for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its reactive halogen and nitro groups for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized pyridine-based ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as conductive polymers and molecular semiconductors, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-Bromo-5-Nitropyridine-2-Carboxylic Acid
CAS No.	1211578-33-4
Molecular Formula	C6H3BrN2O4
Molecular Weight	247.00 g/mol
Synonyms	2-Bromo-3-nitropyridine-6-carboxylic acid; 6-Bromo-5-nitro-2-pyridinecarboxylic acid; 5-Nitro-6-bromopicolinic acid; 2-Pyridinecarboxylic acid, 6-bromo-5-nitro-; Picolinic acid, 6-bromo-5-nitro-; 6-Bromo-5-nitropicolinic acid; (6-Bromo-5-nitropyridin-2-yl)formic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Nitropyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.