Description

3-Bromo-5-Fluoro-2-Methyl-Pyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which enables precise molecular modifications in complex chemical architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its halogenated pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for constructing specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials that require specific halogenated heterocyclic units.
• Custom Synthesis and Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Bromo-5-Fluoro-2-Methyl-Pyridine
CAS No.	1211542-29-8
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	3-Bromo-5-fluoro-2-picoline; 2-Methyl-3-bromo-5-fluoropyridine; 5-Fluoro-3-bromo-2-methylpyridine; 2-Picoline, 3-bromo-5-fluoro-; 3-Bromo-5-fluoro-2-methylpyridine; Pyridine, 3-bromo-5-fluoro-2-methyl-; 1211542-29-8 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Fluoro-2-Methyl-Pyridine is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.