Description

2-Chloro-5-(Trifluoromethyl)Pyridin-4-Ol is a high-value pyridine derivative and a versatile chemical building block prized for its unique halogenated and trifluoromethylated structure. This compound is essential for advanced synthesis, particularly in the development of novel active ingredients where its specific substitution pattern enables precise molecular tuning. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents. Our supply ensures consistent high purity and reliable availability for critical global R&D and manufacturing processes.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Serves as a crucial precursor in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyridine moiety.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to construct complex ligands for transition metal complexes.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or electronic chemicals, where its structural properties are beneficial.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse client projects.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethyl)Pyridin-4-Ol
CAS No.	1211541-22-8
Molecular Formula	C6H3ClF3NO
Molecular Weight	197.54 g/mol
Synonyms	4-Hydroxy-2-chloro-5-(trifluoromethyl)pyridine; 2-Chloro-5-(trifluoromethyl)-4-pyridinol; 2-Chloro-5-trifluoromethylpyridin-4-ol; 2-Chloro-5-(trifluoromethyl)-4-hydroxypyridine; 4-Pyridinol, 2-chloro-5-(trifluoromethyl)-; 2-Chloro-5-(trifluoromethyl)-4(1H)-pyridinone (Tautomeric Form)
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-(Trifluoromethyl)Pyridin-4-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting purity, identity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.