Description

5-Bromo-6-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its core value lies in the strategic combination of a bromo substituent and a trifluoromethyl group on the pyridine scaffold, offering versatile sites for further functionalization and introducing desirable physicochemical properties. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients. Its structure makes it a key intermediate in the development of candidates for drug discovery and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, library synthesis, and exploring new chemical spaces in medicinal and synthetic chemistry.
• Ligand and Catalyst Design: Utilized to construct complex chelating ligands or organocatalysts for asymmetric synthesis and metal-catalyzed cross-coupling reactions.

Basic Information

Product Name	5-Bromo-6-(Trifluoromethyl)Pyridine-2-Carboxylic Acid
CAS No.	1211541-06-8
Molecular Formula	C7H3BrF3NO2
Molecular Weight	269.99 g/mol
Synonyms	2-Pyridinecarboxylic acid, 5-bromo-6-(trifluoromethyl)-; 5-Bromo-6-(trifluoromethyl)picolinic acid; 5-Bromo-6-trifluoromethylpyridine-2-carboxylic acid; 6-Trifluoromethyl-5-bromopyridine-2-carboxylic acid; 5-Bromo-6-trifluoromethyl-2-pyridinecarboxylic acid; 5-Bromo-6-(trifluoromethyl)-2-pyridinecarboxylic acid; 1211541-06-8
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.