Description

5-(Difluoromethyl)Picolinonitrile is a high-value, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a difluoromethyl group and a nitrile moiety, makes it an essential intermediate for creating novel compounds with tailored properties. This product is primarily targeted at research and development teams in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of new generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms to enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science: Employed in the research of advanced organic electronic materials, such as organic semiconductors and liquid crystals, due to its electron-withdrawing characteristics.
• Chemical Biology Probe Synthesis: Utilized to create fluorinated probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	5-(Difluoromethyl)Picolinonitrile
CAS No.	1211540-57-6
Molecular Formula	C7H4F2N2
Molecular Weight	154.12 g/mol
Synonyms	5-(Difluoromethyl)-2-cyanopyridine; 2-Cyano-5-(difluoromethyl)pyridine; 5-(Difluoromethyl)-2-pyridinecarbonitrile; Picolinonitrile, 5-(difluoromethyl)-; 1211540-57-6
EINECS	Contact for details

Quality Control

Our 5-(Difluoromethyl)Picolinonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC), identity confirmation, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.