Description

5-Bromo-4-Chloro-2-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring bromine, chlorine, and trifluoromethyl substituents, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the halogen and fluorine atoms contribute to biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the functionalized pyridine core into more complex molecular architectures.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-directed projects requiring this specific halogenated scaffold.

Basic Information

Product Name	5-Bromo-4-Chloro-2-(Trifluoromethyl)Pyridine
CAS No.	1211537-20-0
Molecular Formula	C6H2BrClF3N
Molecular Weight	260.44 g/mol
Synonyms	4-Chloro-5-bromo-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-5-bromo-4-chloropyridine; 5-Bromo-4-chloro-2-trifluoromethylpyridine; Pyridine, 5-bromo-4-chloro-2-(trifluoromethyl)-; 1211537-20-0
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for our advanced intermediates. Our standard grade for 5-Bromo-4-Chloro-2-(Trifluoromethyl)Pyridine typically meets a purity specification of ≥97% (by HPLC), with identity confirmed by spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment. We can support development projects with custom purity grades and analytical support upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.