Description

6-Bromo-3-Chloro-2-(Trifluoromethyl)Pyridine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the halogenated pyridine core.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and specialty polymers.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for sequential Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	6-Bromo-3-Chloro-2-(Trifluoromethyl)Pyridine
CAS No.	1211536-90-1
Molecular Formula	C7H2BrClF3N
Molecular Weight	274.45 g/mol
Synonyms	2-Bromo-5-chloro-6-(trifluoromethyl)pyridine; 3-Chloro-6-bromo-2-(trifluoromethyl)pyridine; 6-Bromo-3-chloro-2-trifluoromethylpyridine; Pyridine, 6-bromo-3-chloro-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-6-bromo-3-chloropyridine; 6-Bromo-3-chloro-α,α,α-trifluoro-2-picoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloro-2-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.