Description

2-Bromo-6-(1,1-Difluoroethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and difluoroalkyl substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the difluoroethyl group for enhanced bioactivity and environmental stability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Chemical Biology Probes: Utilized in medicinal chemistry for creating labeled compounds and molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated pyridine motifs.

Basic Information

Item	Detail
Product Name	2-Bromo-6-(1,1-Difluoroethyl)Pyridine
CAS No.	1211535-69-1
Molecular Formula	C7H6BrF2N
Molecular Weight	222.03 g/mol
Synonyms	6-(1,1-Difluoroethyl)-2-bromopyridine; 2-Bromo-6-(1,1-difluoroethyl)pyridine; 2-Bromo-6-(α,α-difluoroethyl)pyridine; 2-Bromo-6-(difluoroethyl)pyridine; Pyridine, 2-bromo-6-(1,1-difluoroethyl)-; 1211535-69-1; 2-Br-6-(1,1-F2Et)Py
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(1,1-Difluoroethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.