Description

5-Fluoro-2-Methyl-Nicotinic Acid is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in enabling the precise introduction of both fluorine and a carboxylic acid functional group, which are pivotal for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and liquid crystals.
• Chemical Biology Probes: Utilized to create fluorinated analogs for metabolic pathway studies and protein binding assays.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for bespoke chemical synthesis services targeting niche applications.

Basic Information

Product Name	5-Fluoro-2-Methyl-Nicotinic Acid
CAS No.	1211534-44-9
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	5-Fluoro-2-methylpyridine-3-carboxylic acid; 3-Carboxy-5-fluoro-2-methylpyridine; 2-Methyl-5-fluoronicotinic acid; 5-Fluoro-2-picolinic acid; 5-Fluoro-2-methyl-3-pyridinecarboxylic acid; 1211534-44-9; 5-Fluoro-2-methylnicotinic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methyl-Nicotinic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.