Description

2-tert-Butyl-5-Chloronicotinaldehyde is a versatile and high-purity chemical building block, specifically a substituted nicotinaldehyde derivative. This compound is valued for its role as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex pyridine or nicotinic acid derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the tert-butyl and chloro substituents impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological systems and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	2-tert-Butyl-5-Chloronicotinaldehyde
CAS No.	1211534-07-4
Molecular Formula	C10H12ClNO
Molecular Weight	197.66 g/mol
Synonyms	5-Chloro-2-(tert-butyl)pyridine-3-carbaldehyde; 2-(1,1-Dimethylethyl)-5-chloro-3-pyridinecarboxaldehyde; 5-Chloro-2-tert-butylnicotinaldehyde; 3-Formyl-5-chloro-2-tert-butylpyridine; 2-tert-Butyl-5-chloropyridine-3-carboxaldehyde; 5-Chloro-2-(tert-butyl)nicotinaldehyde; 2-tert-Butyl-5-chloro-3-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-tert-Butyl-5-Chloronicotinaldehyde is manufactured and tested under a strict quality management system. We guarantee high purity and consistency to meet the exacting standards of research and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize repeated exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.