Description

Benzyl 6-Amino-2-Azaspiro[3.3]Heptane-2-Carboxylate is a high-value, spirocyclic building block of significant interest in modern pharmaceutical research and development. This compound serves as a critical intermediate for constructing novel, three-dimensional molecular architectures, which are highly sought after to improve drug-like properties such as metabolic stability and target selectivity. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Scaffold: Used to introduce the rigid, three-dimensional 2-azaspiro[3.3]heptane motif into drug discovery libraries to explore new chemical space and improve pharmacokinetic profiles.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scalable synthesis of complex drug molecules under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probe Synthesis: Employed in the creation of tool compounds and molecular probes for target validation and mechanistic studies in biological systems.
• Agrochemical Research: Potential application as a building block for novel crop protection agents requiring specific steric and electronic properties.
• Academic Research: Used in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Benzyl 6-Amino-2-Azaspiro[3.3]Heptane-2-Carboxylate
CAS No.	1211533-81-1
Molecular Formula	C14H18N2O2
Molecular Weight	246.31 g/mol
Synonyms	Benzyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate; 2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-amino-, benzyl ester; 6-Amino-2-azaspiro[3.3]heptane-2-carboxylic acid benzyl ester; Benzyl 6-amino-2-azaspiro[3.3]heptyl-2-carboxylate; 2-Azaspiro[3.3]heptane-6-amine, 2-(benzyloxycarbonyl)-; Z-6-Amino-2-azaspiro[3.3]heptane; Cbz-6-Amino-2-azaspiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our Benzyl 6-Amino-2-Azaspiro[3.3]Heptane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. For advanced applications, we offer material produced under GMP guidelines and can support regulatory filings with relevant documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and handling. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.