Description

2-Chloro-5-(Trifluoromethyl)-3-Vinylpyridine is a high-value, multi-functional pyridine derivative and a key advanced intermediate in modern organic synthesis. Its molecular architecture, featuring a reactive vinyl group, a chloro substituent, and a trifluoromethyl group, makes it an indispensable building block for constructing complex molecules with tailored properties. This compound is primarily sought by R&D and process development teams in the agrochemical and pharmaceutical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A critical precursor for the synthesis of next-generation insecticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry research for constructing drug candidates, particularly in kinase inhibitor and antiviral compound libraries.
• Ligand Synthesis: Serves as a starting material for creating novel nitrogen-containing ligands used in catalysis and material science.
• Functional Material Development: Incorporated into polymers and specialty chemicals to impart unique surface properties, durability, and chemical resistance.
• Cross-Coupling Reactions: The vinyl and chloro groups make it a versatile substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethyl)-3-Vinylpyridine
CAS No.	1211532-67-0
Molecular Formula	C8H5ClF3N
Molecular Weight	207.58 g/mol
Synonyms	3-Ethenyl-2-chloro-5-(trifluoromethyl)pyridine; 2-Chloro-3-vinyl-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-chloro-3-vinylpyridine; 2-Chloro-5-trifluoromethyl-3-vinylpyridine; 3-Vinyl-2-chloro-5-trifluoromethylpyridine; 1211532-67-0; CTVP
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-(Trifluoromethyl)-3-Vinylpyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.