Description

5-Bromo-4-Fluoro-2-Methylpyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, multi-functional scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists in fine chemical, pharmaceutical, and agrochemical industries seeking to introduce bromine and fluorine substituents into heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated pyridines.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Chemical Biology & Proteomics: Employed as a versatile tag or linker molecule in probe development for studying biological systems.
• Cross-Coupling Reactions: Acts as a valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Bromo-4-Fluoro-2-Methylpyridine
CAS No.	1211532-14-7
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	2-Methyl-5-bromo-4-fluoropyridine; 4-Fluoro-5-bromo-2-picoline; 5-Bromo-4-fluoro-2-picoline; 2-Picoline, 5-bromo-4-fluoro-; 4-Fluoro-5-bromo-2-methylpyridine; Pyridine, 5-bromo-4-fluoro-2-methyl-
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Fluoro-2-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.