Description

2-(Chloromethyl)-6-(Difluoromethyl)Pyridine is a versatile halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a chloromethyl and a difluoromethyl group, makes it a highly valuable intermediate for constructing complex molecules with tailored properties. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries seeking to introduce specific fluorinated motifs and reactive handles into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing anti-infective properties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized pyridine-based ligands used in catalysis and material science.
• Fluorinated Building Block: Employed in medicinal chemistry and material science to incorporate fluorine atoms, which can significantly alter a molecule's lipophilicity, metabolic stability, and binding affinity.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-(Chloromethyl)-6-(Difluoromethyl)Pyridine
CAS No.	1211525-99-3
Molecular Formula	C7H6ClF2N
Molecular Weight	177.58 g/mol
Synonyms	6-(Difluoromethyl)-2-(chloromethyl)pyridine; 2-Chloromethyl-6-difluoromethylpyridine; (6-(Difluoromethyl)pyridin-2-yl)methyl chloride; 2-Pyridinemethanol, 6-(difluoromethyl)-, chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(Chloromethyl)-6-(Difluoromethyl)Pyridine is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.