Description

2,3-Dibromo-5-Methoxypyridine is a halogenated pyridine derivative serving as a versatile and high-value synthetic intermediate. This compound is particularly valued for its reactivity, enabling the introduction of the dibromo-methoxypyridine moiety into complex molecular architectures. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for use in cross-coupling reactions, nucleophilic substitutions, and as a building block for active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging its halogenated structure for further functionalization.
• Material Science Research: Employed as a precursor for creating functionalized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and Negishi couplings to form biaryl and heterobiaryl structures central to many functional molecules.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	2,3-Dibromo-5-Methoxypyridine
CAS No.	1211521-89-9
Molecular Formula	C6H5Br2NO
Molecular Weight	266.92 g/mol
Synonyms	5-Methoxy-2,3-dibromopyridine; 2,3-Dibromo-5-methoxypyridine; Pyridine, 2,3-dibromo-5-methoxy-; 1211521-89-9
EINECS	Contact for details

Quality Control

Our 2,3-Dibromo-5-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to quality supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.