Description

Pyridine, 2-Bromo-3-Methyl-5-(Trifluoromethyl)- is a high-value, multi-functional halogenated pyridine derivative, distinguished by its bromine and trifluoromethyl substituents. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry, enabling the introduction of complex fluorinated motifs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging the biological activity of the pyridine core and fluorine atoms.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and liquid crystals.
• Fluorine Chemistry Building Block: Essential for introducing the trifluoromethyl group into complex molecules, a common strategy in medicinal chemistry to modulate lipophilicity and metabolic stability.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects.

Basic Information

Product Name	Pyridine, 2-Bromo-3-Methyl-5-(Trifluoromethyl)-
CAS No.	1211520-05-6
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	2-Bromo-3-methyl-5-(trifluoromethyl)pyridine; 3-Methyl-5-(trifluoromethyl)-2-bromopyridine; 2-Bromo-3-methyl-5-trifluoromethylpyridine; 5-(Trifluoromethyl)-2-bromo-3-methylpyridine; 2-Bromo-3-methyl-5-(trifluoromethyl)pyridine (CAS 1211520-05-6); Bromo-methyl-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our production of Pyridine, 2-Bromo-3-Methyl-5-(Trifluoromethyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.