Description

Methyl 6-Chloro-5-Cyanonicotinate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic positioning of reactive functional groups—chloro, cyano, and ester—which enable precise derivatization for creating complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those with nicotinic acid or pyridine-based scaffolds, for therapeutic areas such as oncology and CNS disorders.
• Agrochemical Synthesis: Serves as a versatile building block for developing novel herbicides, insecticides, and fungicides, leveraging its halogen and nitrile functionalities.
• Ligand and Catalyst Development: Used in the research and preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds due to its conjugated pyridine core.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise functionalization on a pyridine ring.

Basic Information

Product Name	Methyl 6-Chloro-5-Cyanonicotinate
CAS No.	1211520-03-4
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	Methyl 6-chloro-5-cyanopyridine-3-carboxylate; 5-Cyano-6-chloronicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 6-chloro-5-cyano-, methyl ester; 6-Chloro-5-cyano-3-pyridinecarboxylic acid methyl ester; Methyl 6-chloro-5-cyano-3-pyridinecarboxylate; Methyl 6-chloro-5-cyano-3-picolinate
EINECS	Contact for details

Quality Control

Our Methyl 6-Chloro-5-Cyanonicotinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.