Description

3-Chloro-5-Methylpicolinonitrile is a versatile and high-value pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated and nitrile-substituted structure makes it an essential building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of functional organic materials, including liquid crystals and electronic chemicals.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and process development.

Basic Information

Product Name	3-Chloro-5-Methylpicolinonitrile
CAS No.	1211518-69-2
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	3-Chloro-5-methylpyridine-2-carbonitrile; 2-Cyano-3-chloro-5-methylpyridine; 5-Methyl-3-chloropicolinonitrile; 3-Chloro-5-picolinonitrile; 3-Chloro-5-methyl-2-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Methylpicolinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.