Description

4-Bromo-5-Chloro-3-Hydroxypyridine is a halogenated pyridine derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its molecular structure makes it a critical building block for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), specialty chemicals, and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for creating functionalized polymers, ligands for metal-organic frameworks (MOFs), and other advanced materials.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging reagent in the development of chemical probes and enzyme inhibitors.
• Organic Synthesis: A versatile substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization to create diverse chemical libraries.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-directed projects.

Basic Information

Product Name	4-Bromo-5-Chloro-3-Hydroxypyridine
CAS No.	1211517-85-9
Molecular Formula	C5H3BrClNO
Molecular Weight	208.44 g/mol
Synonyms	3-Hydroxy-4-bromo-5-chloropyridine; 5-Chloro-4-bromopyridin-3-ol; 4-Bromo-5-chloro-3-pyridinol; 3-Pyridinol, 4-bromo-5-chloro-; 4-Bromo-5-chloro-3-hydroxypyridine; 4-Bromo-5-chloro-3-pyridol
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Chloro-3-Hydroxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.