Description

2-Chloro-5-Nitro-3-Pyridinylethanone is a high-purity, versatile pyridine derivative building block essential for advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its nitro and chloro substituents for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and photoactive compounds due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses serving the life sciences sector.
• Academic and Industrial R&D: Utilized in research laboratories for method development and exploring new chemical reactions involving halogenated nitro-heterocycles.

Basic Information

Product Name	2-Chloro-5-Nitro-3-Pyridinylethanone
CAS No.	1211517-54-2
Molecular Formula	C7H5ClN2O3
Molecular Weight	200.58 g/mol
Synonyms	1-(2-Chloro-5-nitropyridin-3-yl)ethanone; 3-Acetyl-2-chloro-5-nitropyridine; 2-Chloro-5-nitro-3-acetylpyridine; Ethanone, 1-(2-chloro-5-nitro-3-pyridinyl)-; 2-Chloro-5-nitro-pyridin-3-yl-methyl-ketone; 3-Pyridinylethanone, 2-chloro-5-nitro-; 2-Chloro-5-nitronicotinoyl methyl
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Nitro-3-Pyridinylethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality documentation to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to prevent decomposition. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.