Description

Methyl 5-Hydroxy-3-Methylpicolinate is a high-purity, functionalized picolinate ester serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and complex agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific heterocyclic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal catalysis and coordination chemistry.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other performance chemicals requiring specific pyridine-based structures.
• Material Science Research: Monomer or functional additive in the development of advanced polymers and organic electronic materials.
• Academic and Contract Research: Essential reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	Methyl 5-Hydroxy-3-Methylpicolinate
CAS No.	1211516-93-6
Molecular Formula	C8H9NO3
Molecular Weight	167.16 g/mol
Synonyms	5-Hydroxy-3-methylpyridine-2-carboxylic acid methyl ester; Methyl 5-hydroxy-3-methyl-2-pyridinecarboxylate; 3-Methyl-5-hydroxypicolinic acid methyl ester; 2-Pyridinecarboxylic acid, 5-hydroxy-3-methyl-, methyl ester; Methyl 3-methyl-5-hydroxypicolinate
EINECS	Contact for details

Quality Control

Our Methyl 5-Hydroxy-3-Methylpicolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.