Description

2-Bromo-3-Chloro-6-Methoxy-Pyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drug candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold or labeling reagent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Buchwald-Hartwig amination, facilitating carbon-carbon and carbon-heteroatom bond formation.
• Ligand Synthesis: Useful for constructing complex nitrogen-containing ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	2-Bromo-3-Chloro-6-Methoxy-Pyridine
CAS No.	1211515-77-3
Molecular Formula	C6H5BrClNO
Molecular Weight	222.46 g/mol
Synonyms	3-Chloro-2-bromo-6-methoxypyridine; 6-Methoxy-2-bromo-3-chloropyridine; 2-Bromo-3-chloro-6-methoxypyridine; Pyridine, 2-bromo-3-chloro-6-methoxy-; 1211515-77-3
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Chloro-6-Methoxy-Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.