Description

5,6,7,8-Tetrahydro-1H-[1,6]Naphthyridin-2-One Hydrochloride is a high-purity organic salt, recognized as a key pharmaceutical intermediate and building block in advanced chemical synthesis. Its value lies in its precise molecular structure, which is critical for research and development in life sciences, particularly for creating novel active pharmaceutical ingredients (APIs). This compound is essential for medicinal chemists and process development scientists working in pharmaceutical R&D, agrochemical discovery, and advanced material science.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Agrochemical Synthesis: An intermediate in the development of advanced crop protection agents and pesticides.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory organic synthesis and heterocyclic chemistry studies.
• Process Chemistry Development: Used to scale up and optimize synthetic routes for cost-effective and robust manufacturing processes.

Basic Information

Product Name	5,6,7,8-Tetrahydro-1H-[1,6]Naphthyridin-2-One Hydrochloride
CAS No.	1211505-91-7
Molecular Formula	C8H11ClN2O
Molecular Weight	186.64 g/mol
Synonyms	1,2,3,4-Tetrahydro-[1,6]naphthyridin-2-one hydrochloride; 5,6,7,8-Tetrahydro-1H-[1,6]naphthyridin-2(3H)-one hydrochloride; 2-Oxo-1,2,3,4-tetrahydro-1,6-naphthyridine hydrochloride; THN Hydrochloride; [1,6]Naphthyridin-2-one, 5,6,7,8-tetrahydro-1H-, hydrochloride; Tetrahydro[1,6]naphthyridinone HCl
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-1H-[1,6]Naphthyridin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure compliance with pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.