Description

5-Bromo-3-Ethynylpyridin-2-Amine is a high-value, multi-functional pyridine derivative featuring both bromo and ethynyl substituents, making it a versatile building block for complex molecular synthesis. Its core value lies in enabling precise structural modifications in advanced pharmaceutical and agrochemical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries seeking to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in constructing novel active ingredients for crop protection products, leveraging its halogen and alkyne functionality.
• Chemical Biology & Proteomics: Serves as a click chemistry handle (via the ethynyl group) for bioconjugation, labeling, and probe development.
• Material Science Research: Acts as a precursor for organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized pyridine cores.
• Academic & R&D Laboratories: Employed in methodological studies and novel reaction development in organic chemistry.

Basic Information

Item	Detail
Product Name	5-Bromo-3-Ethynylpyridin-2-Amine
CAS No.	1210838-82-6
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	2-Amino-5-bromo-3-ethynylpyridine; 3-Ethynyl-5-bromopyridin-2-amine; 5-Bromo-3-ethynyl-2-pyridinamine; 5-Bromo-3-ethynyl-2-aminopyridine; (5-Bromo-2-aminopyridin-3-yl)acetylene
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Ethynylpyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with your specified requirements. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.