Description

n-(4-((1R,3S,5S)-3-Amino-5-Methylcyclohexyl)Pyridin-3-Yl)-6-(2,6-Difluorophenyl)-5-Fluoropicolinamide is a high-purity, advanced pharmaceutical intermediate with a complex, stereochemically defined structure. This compound is critical for research and development in medicinal chemistry, particularly for targeting specific biological pathways. It is primarily needed by pharmaceutical companies, biotechnology research firms, and academic institutions engaged in the synthesis of novel therapeutic agents, especially within oncology and targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel, targeted small-molecule drug candidates.
• Oncology Research: Used in the development of potential kinase inhibitors and other cancer therapeutics.
• Medicinal Chemistry R&D: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Potential tool compound for probing enzyme function and cellular signaling pathways.
• Preclinical Development: Supplied for use in the production of batches for pharmacological and toxicological studies.
• Contract Manufacturing: Sourced by CDMOs for cGMP-compliant synthesis of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	n-(4-((1R,3S,5S)-3-Amino-5-Methylcyclohexyl)Pyridin-3-Yl)-6-(2,6-Difluorophenyl)-5-Fluoropicolinamide
CAS No.	1210608-43-7
Molecular Formula	C24H23F3N4O
Molecular Weight	440.46 g/mol
Synonyms	6-(2,6-Difluorophenyl)-N-[4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]-3-pyridinyl]-5-fluoropyridine-2-carboxamide; (1R,3S,5S)-N-(4-(3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide; UNII-9QK2K7S8XG; 9QK2K7S8XG; BDBM50389319; AKOS025147065; ZINC000103486756; CHEMBL3186662
EINECS	Contact for details

Quality Control

Our n-(4-((1R,3S,5S)-3-Amino-5-Methylcyclohexyl)Pyridin-3-Yl)-6-(2,6-Difluorophenyl)-5-Fluoropicolinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure high chemical and isomeric purity suitable for advanced research. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.