Description

5-(5-Bromo-1H-Pyrrolo-[2,3-B]Pyridin-3-Yl)-n-[(3-Methoxyphenyl)Methyl]-1,3,4-Oxadiazol-2-Amine is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is a key building block in modern medicinal chemistry, valued for its complex heterocyclic structure which is integral to creating novel bioactive molecules. It is primarily sought after by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the synthesis of new therapeutic agents, particularly in oncology and targeted drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Research: Used in the development and optimization of small-molecule kinase inhibitors, a major class of targeted cancer therapies.
• Medicinal Chemistry & Lead Optimization: Employed by R&D teams for structure-activity relationship (SAR) studies to improve drug potency, selectivity, and pharmacokinetic properties.
• Biochemical Assay Development: Utilized as a reference standard or probe compound in high-throughput screening (HTS) and biochemical assays.
• Academic Research: Supports chemical biology and drug discovery projects in university and institutional laboratories.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) specializing in custom synthesis from milligram to kilogram scale.

Basic Information

Product Name	5-(5-Bromo-1H-Pyrrolo-[2,3-B]Pyridin-3-Yl)-n-[(3-Methoxyphenyl)Methyl]-1,3,4-Oxadiazol-2-Amine
CAS No.	1210437-59-4
Molecular Formula	C₁₇H₁₄BrN₅O₂
Molecular Weight	400.23 g/mol
Synonyms	5-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[(3-methoxyphenyl)methyl]-1,3,4-oxadiazol-2-amine; 5-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-(3-methoxybenzyl)-1,3,4-oxadiazol-2-amine; 1,3,4-Oxadiazol-2-amine, 5-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[(3-methoxyphenyl)methyl]-; N-(3-Methoxybenzyl)-5-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-1,3,4-oxadiazol-2-amine; CAS 1210437-59-4
EINECS	Contact for details

Quality Control

Our 5-(5-Bromo-1H-Pyrrolo-[2,3-B]Pyridin-3-Yl)-n-[(3-Methoxyphenyl)Methyl]-1,3,4-Oxadiazol-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere at lower temperatures (e.g., -20°C) to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.