Description

(1R,3R,6S)-Ethyl 7-Oxabicyclo[4.1.0]heptane-3-carboxylate is a high-purity, chiral oxirane-fused bicyclic compound that serves as a critical advanced intermediate in sophisticated organic synthesis. Its unique stereochemistry and strained ring system make it a valuable building block for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides requiring specific stereochemical configurations for optimal activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties derived from its rigid bicyclic structure.
• Academic & R&D Laboratories: Employed in methodological studies and the total synthesis of complex natural products.

Basic Information

Product Name	(1R,3R,6S)-Ethyl 7-Oxabicyclo[4.1.0]heptane-3-carboxylate
CAS No.	1210348-12-1
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	Ethyl (1R,3R,6S)-7-oxabicyclo[4.1.0]heptane-3-carboxylate; (-)-(1R,3R,6S)-Ethyl 7-oxabicyclo[4.1.0]heptane-3-carboxylate; 7-Oxabicyclo[4.1.0]heptane-3-carboxylic acid, ethyl ester, (1R,3R,6S)-; Chiral Ethyl 7-Oxabicyclo[4.1.0]heptane-3-carboxylate; (1R,3R,6S)-Ethyl 7-oxanorbornane-3-carboxylate; (1R,3R,6S)-Ethyl 7-oxabicyclo[4.1.0]hept-3-ylcarboxylate
EINECS	Contact for details

Quality Control

Our (1R,3R,6S)-Ethyl 7-Oxabicyclo[4.1.0]heptane-3-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and enantiomeric excess meet the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) detailing specifications such as chiral purity (HPLC), chemical purity (GC/HPLC), and residual solvents (GC) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.