Description

3-Bromo-5-(1H-Pyrazol-1-yl)pyridine is a high-value heterocyclic building block featuring a bromine substituent and a pyrazole ring, which are critical for constructing complex molecular architectures. This compound is essential for medicinal chemistry and materials science research, enabling the synthesis of novel active pharmaceutical ingredients (APIs) and functional organic materials. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for lead optimization and scaffold diversification.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor modulators, and other small molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Chemical Biology: Employed in the creation of molecular probes and tool compounds for studying biological pathways.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Library Synthesis: A versatile scaffold for generating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	3-Bromo-5-(1H-Pyrazol-1-yl)pyridine
CAS No.	1209458-66-1
Molecular Formula	C8H6BrN3
Molecular Weight	224.06 g/mol
Synonyms	3-Bromo-5-(1H-pyrazol-1-yl)pyridine; 3-Bromo-5-(pyrazol-1-yl)pyridine; 5-(1H-Pyrazol-1-yl)-3-bromopyridine; Pyridine, 3-bromo-5-(1H-pyrazol-1-yl)-; 1-(5-Bromopyridin-3-yl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(1H-Pyrazol-1-yl)pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our standard quality commitment aligns with cGMP principles for advanced intermediates, ensuring suitability for use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.