Description

1'-(5-Bromo-6-Chloro-4-(Trifluoromethyl)Pyridin-2-Yl)Piperazine Hydrobromide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block with a unique halogenated and trifluoromethylated pyridine core. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting innovative therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its halogenated and piperazine functionalities.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Supplied to contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Agrochemical Research: Potential application as an intermediate in the development of new agrochemicals with specific biological activity.

Basic Information

Product Name	1'-(5-Bromo-6-Chloro-4-(Trifluoromethyl)Pyridin-2-Yl)Piperazine Hydrobromide
CAS No.	1208081-40-6
Molecular Formula	C11H11BrClF3N3•HBr
Molecular Weight	Contact for details
Synonyms	5-Bromo-6-chloro-2-(piperazin-1-yl)-4-(trifluoromethyl)pyridine hydrobromide; 2-(1-Piperazinyl)-5-bromo-6-chloro-4-(trifluoromethyl)pyridine hydrobromide; 1-(5-Bromo-6-chloro-4-(trifluoromethyl)pyridin-2-yl)piperazine hydrobromide; 5-Bromo-6-chloro-4-(trifluoromethyl)-2-piperazin-1-ylpyridine hydrobromide; CAS 1208081-40-6
EINECS	Contact for details

Quality Control

Our 1'-(5-Bromo-6-Chloro-4-(Trifluoromethyl)Pyridin-2-Yl)Piperazine Hydrobromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.