Description

2-Chloro-6-Methoxy-Pyridine-3-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its dual reactive sites make it an indispensable intermediate for constructing complex molecules with high precision and efficiency. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of sulfonamide-based active pharmaceutical ingredients (APIs), including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the production of modern herbicides, fungicides, and insecticides, where the pyridine-sulfonyl moiety contributes to biological activity.
• Material Science Research: Employed in the synthesis of functional polymers, ligands for catalysis, and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A pivotal reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of chemical probes to study biological systems.

Basic Information

Product Name	2-Chloro-6-Methoxy-Pyridine-3-Sulfonyl Chloride
CAS No.	1208081-26-8
Molecular Formula	C6H5Cl2NO3S
Molecular Weight	246.08 g/mol
Synonyms	2-Chloro-6-methoxypyridine-3-sulfonyl chloride; 3-Pyridinesulfonyl chloride, 2-chloro-6-methoxy-; 2-Chloro-6-methoxy-3-pyridinesulfonyl chloride; 2-Chloro-6-methoxypyridine-3-sulfonylchloride; 1208081-26-8
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-6-Methoxy-Pyridine-3-Sulfonyl Chloride adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets your precise research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.