Description

Ethyl 2-Bromo-5-Iodobenzoate is a high-purity halogenated aromatic ester building block, essential for advanced organic synthesis and pharmaceutical research. Its unique bifunctional halogen pattern offers versatile reactivity for selective cross-coupling reactions and molecular diversification. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the bromine and iodine substituents enable specific biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings, allowing for the sequential introduction of diverse functional groups.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for imaging and diagnostic applications due to its halogen handles.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and catalysis research.

Basic Information

Product Name	Ethyl 2-Bromo-5-Iodobenzoate
CAS No.	1208075-44-8
Molecular Formula	C9H8BrIO2
Molecular Weight	354.97 g/mol
Synonyms	Benzoic acid, 2-bromo-5-iodo-, ethyl ester; Ethyl 2-bromo-5-iodobenzoate; 2-Bromo-5-iodobenzoic acid ethyl ester; Ethyl o-bromo-p-iodobenzoate; 1208075-44-8; Ethyl 2-Br-5-I-Benzoate; 5-Iodo-2-bromobenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromo-5-Iodobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles for research-grade materials to support your critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.