Description

4-Chloro-3-Iodo-Benzoic Acid Ethyl Ester is a high-purity halogenated aromatic ester, a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Ligand & Catalyst Synthesis: Serves as a starting material for creating sophisticated ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology: Useful as a probe or tagging reagent due to the reactivity of the iodine atom for further functionalization.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-Chloro-3-Iodo-Benzoic Acid Ethyl Ester
CAS No.	1208074-81-0
Molecular Formula	C9H8ClIO2
Molecular Weight	310.52 g/mol
Synonyms	Ethyl 4-Chloro-3-iodobenzoate; Benzoic acid, 4-chloro-3-iodo-, ethyl ester; 4-Chloro-3-iodobenzoic acid ethyl ester; 3-Iodo-4-chlorobenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-3-Iodo-Benzoic Acid Ethyl Ester is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.