Description

S-1-Pyrrolidinecarboxylic Acid, 2-(6-Bromo-1H-Benzimidazol-2-Yl)-, 1,1-Dimethyleth is a high-value, multi-functional heterocyclic building block that combines a benzimidazole core with a proline derivative. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially protease inhibitors and kinase inhibitors.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and plant growth regulators.
• Ligand Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Material Science: Component in the research of organic semiconductors and advanced polymers.
• Bioconjugation: Useful in creating linkers for antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Chemical Biology: Employed as a molecular probe or scaffold in the study of enzyme mechanisms and protein interactions.

Basic Information

Product Name	S-1-Pyrrolidinecarboxylic Acid, 2-(6-Bromo-1H-Benzimidazol-2-Yl)-, 1,1-Dimethyleth
CAS No.	1208007-67-3
Molecular Formula	C16H20BrN3O2
Molecular Weight	366.25 g/mol
Synonyms	2-(6-Bromo-1H-benzimidazol-2-yl)-1-(tert-butoxycarbonyl)pyrrolidine; (S)-1-(tert-Butoxycarbonyl)-2-(6-bromo-1H-benzimidazol-2-yl)pyrrolidine; Boc-6-Bromo-L-tryptophan benzimidazole analog; tert-Butyl (S)-2-(6-bromo-1H-benzo[d]imidazol-2-yl)pyrrolidine-1-carboxylate; 6-Bromo-L-Boc-tryptophan benzimidazole; S-Boc-2-(6-Bromo-1H-benzimidazol-2-yl)pyrrolidine
EINECS	Contact for details

Quality Control

Our S-1-Pyrrolidinecarboxylic Acid, 2-(6-Bromo-1H-Benzimidazol-2-Yl)-, 1,1-Dimethyleth is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure compliance with research-grade standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a desiccated environment when not in use. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.