Description

Benzyl 3-Amino-4-Fluoropiperidine-1-Carboxylate is a high-purity, fluorinated piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines a reactive amine group with a fluorine atom and a benzyloxycarbonyl (Cbz) protecting group, enabling precise chemical modifications. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for neurological targets.
• Medicinal Chemistry: Used to introduce the 3-amino-4-fluoropiperidine moiety into lead compounds to modulate bioavailability, potency, and metabolic stability.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides with improved efficacy.
• Chemical Biology Research: Employed as a probe or building block in the study of biological pathways and enzyme inhibition.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals for clients.
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	Benzyl 3-Amino-4-Fluoropiperidine-1-Carboxylate
CAS No.	1207853-07-3
Molecular Formula	C13H17FN2O2
Molecular Weight	252.29 g/mol
Synonyms	1-Cbz-3-Amino-4-fluoropiperidine; Benzyl N-(3-Amino-4-fluoropiperidin-1-yl)carboxylate; 4-Fluoro-3-aminopiperidine-1-carboxylic acid benzyl ester; 3-Amino-4-fluoropiperidine-1-carboxylic acid benzyl ester; 1-(Benzyloxycarbonyl)-3-amino-4-fluoropiperidine; N-Cbz-3-Amino-4-fluoropiperidine; 4-Fluoro-3-aminopiperidine-1-N-Cbz; 1207853-07-3
EINECS	Contact for details

Quality Control

Our Benzyl 3-Amino-4-Fluoropiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.