Description

tert-Butyl 2,6-Diazaspiro[3.3]heptane-2-carboxylate hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a constrained spirocyclic diamine scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for constructing novel drug candidates. It is primarily sought after by pharmaceutical companies and research institutions engaged in the synthesis of small molecule therapeutics, particularly those targeting central nervous system (CNS) disorders and other disease areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Employed as a linker component or part of the ligand structure in the design of bifunctional degrader molecules.
• CNS Drug Discovery: The spirocyclic diamine structure is valuable for creating molecules with potential applications in neurological and psychiatric conditions.
• Chemical Biology Probes: Utilized in the synthesis of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CRMOs) producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl 2,6-Diazaspiro[3.3]heptane-2-carboxylate hydrochloride
CAS No.	1207840-19-4
Molecular Formula	C11H21ClN2O2
Molecular Weight	248.75 g/mol
Synonyms	2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 1,1-dimethylethyl ester, hydrochloride (1:1); tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate HCl; 2-(tert-Butoxycarbonyl)-2,6-diazaspiro[3.3]heptane hydrochloride; 2-Boc-2,6-diazaspiro[3.3]heptane hydrochloride; Boc-2,6-diazaspiro[3.3]heptane HCl; 1,1-Dimethylethyl 2,6-diazaspiro[3.3]heptane-2-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,6-Diazaspiro[3.3]heptane-2-carboxylate hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing comprehensive specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.