Description

6-Bromo-4-Methoxypyrazolo[1,5-A]Pyridine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce complex molecular scaffolds into their synthetic pipelines.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile pyrazolopyridine core.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel crop protection agents and herbicides.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Material Science Research: Investigated as a precursor for organic electronic materials and functional dyes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial APIs.

Basic Information

Product Name	6-Bromo-4-Methoxypyrazolo[1,5-A]Pyridine-3-Carbonitrile
CAS No.	1207836-10-9
Molecular Formula	C9H6BrN3O
Molecular Weight	252.07 g/mol
Synonyms	6-Bromo-4-methoxy-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile; 6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile; 1207836-10-9; 4-Methoxy-6-bromopyrazolo[1,5-a]pyridine-3-carbonitrile; Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-bromo-4-methoxy-; 6-Bromo-4-methoxy-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile; 6-Bromo-4-methoxy-pyrazolo[1,5-a]pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Methoxypyrazolo[1,5-A]Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere where prolonged exposure is expected to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.