Description

2-(p-Tolylsulfonyl)-6-Thia-2-Azaspiro[2.5]Octane is a high-value, specialized spirocyclic sulfonamide building block used in advanced organic synthesis. Its unique spirocyclic scaffold and functional groups make it a critical intermediate for constructing complex molecular architectures with potential biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of protease inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis to explore new chemical space for biological targets.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides, leveraging its spirocyclic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Advanced Material Science: Investigated as a monomer or precursor for creating polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: Employed in methodological development and novel reaction discovery within organic synthesis laboratories.

Basic Information

Product Name	2-(p-Tolylsulfonyl)-6-Thia-2-Azaspiro[2.5]Octane
CAS No.	1207754-86-6
Molecular Formula	C13H17NO2S2
Molecular Weight	283.41 g/mol
Synonyms	2-(4-Methylphenyl)sulfonyl-6-thia-2-azaspiro[2.5]octane; 2-(p-Toluenesulfonyl)-6-thia-2-azaspiro[2.5]octane; 6-Thia-2-azaspiro[2.5]octane, 2-[(4-methylphenyl)sulfonyl]-; 2-Tosyl-6-thia-2-azaspiro[2.5]octane; Spiro[cyclopropane-1,2'-[1,3]thiazolidine], 3-[(4-methylphenyl)sulfonyl]-; 1207754-86-6; 2-(4-Methylbenzenesulfonyl)-6-thia-2-azaspiro[2.5]octane
EINECS	Contact for details

Quality Control

Our production of 2-(p-Tolylsulfonyl)-6-Thia-2-Azaspiro[2.5]Octane adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are fully characterized using advanced analytical techniques, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.