Description

5-Bromo-6-Fluoro-3-Iodopyridin-2-Amine is a highly functionalized pyridine derivative serving as a critical building block in modern synthetic chemistry. Its unique halogenated structure makes it an invaluable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides due to its halogen-substituted pyridine core.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: The iodine and bromine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	5-Bromo-6-Fluoro-3-Iodopyridin-2-Amine
CAS No.	1207625-26-0
Molecular Formula	C5H3BrFIN2
Molecular Weight	316.90 g/mol
Synonyms	2-Amino-5-bromo-6-fluoro-3-iodopyridine; 3-Iodo-5-bromo-6-fluoropyridin-2-amine; 5-Bromo-6-fluoro-3-iodo-2-pyridinamine; 5-Bromo-6-fluoro-3-iodopyridin-2-ylamine; 2-Pyridinamine, 5-bromo-6-fluoro-3-iodo-; 1207625-26-0; 5-Br-6-F-3-I-pyridin-2-amine
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Fluoro-3-Iodopyridin-2-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring the material is suitable for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.