Description

5-Bromo-6-Chloro-3-Iodopyridin-2-Amine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an indispensable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and pesticides with enhanced activity.
• Material Science Research: Used in the creation of organic electronic materials, ligands for catalysis, and functionalized polymers.
• Cross-Coupling Reactions: Serves as a versatile substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive halogen atoms.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation in drug discovery.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development of scalable synthetic routes.

Basic Information

Product Name	5-Bromo-6-Chloro-3-Iodopyridin-2-Amine
CAS No.	1207625-23-7
Molecular Formula	C5H3BrClIN2
Molecular Weight	348.35 g/mol
Synonyms	2-Amino-5-bromo-6-chloro-3-iodopyridine; 3-Iodo-5-bromo-6-chloropyridin-2-amine; 5-Bromo-6-chloro-3-iodo-2-pyridinamine; 5-Bromo-6-chloro-3-iodopyridin-2-ylamine; 2-Pyridinamine, 5-bromo-6-chloro-3-iodo-; 1207625-23-7 (CAS); BCPI
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Chloro-3-Iodopyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.